Search results for "sudden infant death syndrome"

showing 6 items of 6 documents

Territorial Differences in Infant Mortality in Latvia in the First Decade of the Third Millennium

2015

Objective: Infant and child mortality are some of the most substantial indicators of country welfare. Infant mortality (IM) in Latvia is constantly the highest among 25 Member States of the European Union. Since the regaining of independence in 1991, IM has decreased by almost 50%, however, it is still high enough to cause concern that the country will not be able to meet the UN Millennium Development Goals to decrease IM in Latvia by 2015. The Medical Faculty at the University of Latvia has conducted several studies identifying correlations between IM and GDP, total expenditure on health, unemployment and GINI coefficient. It is necessary to identify all IM causes and relationships which h…

AdultPediatricsmedicine.medical_specialtyPopulationRural HealthYoung AdultInfant MortalitymedicineHumansmedia_common.cataloged_instanceRegistriesEuropean unioneducationmedia_commoneducation.field_of_studyInfant NewbornUrban HealthPublic Health Environmental and Occupational HealthInfantGeneral MedicineMillennium Development GoalsSudden infant death syndromeLatviaInfant mortalityEuropeChild mortalityGeographyFemaleResidenceRural areaDemographyCentral European Journal of Public Health
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Heterozygous nonsense SCN5A mutation W822X explains a simultaneous sudden infant death syndrome.

2008

The sudden, unexpected, and unexplained death of both members of a set of healthy twins (simultaneous sudden infant death syndrome (SSIDS)) is defined as a case in which both infants meet the definition of sudden infant death syndrome individually. A search of the world medical literature resulted in only 42 reported cases of SSIDS. We report the case of a pair of identical, male, monozygotic twins, 138 days old, who suddenly died, meeting the full criteria of SSIDS and where a genetic screen was performed, resulting in a heterozygous nonsense SCN5A mutation (W822X) in both twins. Immunohistochemistry was performed on cardiac tissue samples utilizing polyclonal antibodies anti-Na+ CP type V…

MalePathologymedicine.medical_specialtyNav1.5 protein functionv1.5 protein functionmedia_common.quotation_subject2734Nonsense mutationNonsenseNa+ channel functionMuscle ProteinsSocio-culturaleBiology+Nav1.5 protein function; Na+ channel function; SCN5A gene mutation; Simultaneous sudden infant death syndrome; W822X mutation; Codon Nonsense; Diseases in Twins; Humans; Infant; Male; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Sodium Channels; Sudden Infant Death; 2734Sudden deathSodium ChannelsNAV1.5 Voltage-Gated Sodium ChannelPathology and Forensic MedicinePathogenesisSCN5A gene mutationDiseases in TwinsmedicineHumansSimultaneous sudden infant death syndromeSCN5A gene mutationW822X mutationNa+ channel functionNav1.5 protein functionNaSimultaneous sudden infant death syndrome SCN5A gene mutation W822X mutation Na+ channel function Nav1.5 protein function CodonMolecular BiologyCellular localizationmedia_commonSimultaneous sudden infant death syndromeSettore BIO/16 - Anatomia UmanaSimultaneous sudden infant death syndrome SCN5A gene mutation W822X mutation Na+ channel function Nav1.5 protein functionW822X mutationInfantCell BiologyGeneral MedicineSudden infant death syndromeNonsenseTerminal deoxynucleotidyl transferaseCodon NonsenseImmunohistochemistryNa; v; 1.5 protein function; Na; +; channel function; SCN5A gene mutation; Simultaneous sudden infant death syndrome; W822X mutationchannel functionSudden Infant Death
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Clinical experience of a tricomponent acellular pertussis vaccine combined with diphtheria and tetanus toxoids for primary vaccination in 22,505 infa…

1996

Abstract OBJECTIVES: To assess the safety and tolerability of 12 lots of SmithKline Beecham Biologicals' diphtheria-tetanus-tricomponent acellular pertussis vaccine (DTaP) in a large cohort of 22,000 vaccinees, with detailed analyses of reactivity, immunogenicity, and immune response to pertussis toxin in subsets. METHODS: In a prospective, double-blind, multicenter trial in Germany, 22,505 healthy infants received three vaccinations of DTaP at age 3, 4, and 5 months. Serious adverse events were followed for 1 month after each vaccination, and neurologic events for 1 year or longer. Serum IgG antibodies were assayed before vaccination and 1 month after vaccination. RESULTS: After 67,000 dos…

Pediatricsmedicine.medical_specialtyFeverFilamentous haemagglutinin adhesinDouble-Blind MethodSeizuresGermanyMedicineHumansProspective StudiesAdverse effectWhooping coughDiphtheria-Tetanus-Pertussis VaccineEpilepsybusiness.industryTetanusDiphtheriaIncidenceInfantSudden infant death syndromemedicine.diseaseVaccinationPediatrics Perinatology and Child HealthImmunologyPertactinbusinessSpasms InfantileSudden Infant DeathThe Journal of pediatrics
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Declining Incidence of Infantile Hypertrophic Stenosis (IHPS) in Germany 2000-2008

2011

Background: The incidencce of infantile hypertrophic pyloric stenosis (IHPS) is highly variable over time and regionally different. There have been reports of declining incidence in Sweden, the US, Denmark and Scotland. In Sweden, the decline observed was parallel to the declining incidence of Sudden Infant Death Syndrome (SIDS) and was attributed to campaigns against prone sleeping position.

Pediatricsmedicine.medical_specialtyProne sleepingbusiness.industryIncidence (epidemiology)Pediatric researchSudden infant death syndromePediatrics Perinatology and Child HealthEpidemiologymedicineNeonatologyHypertrophic stenosisbusinessHypertrophic Pyloric StenosisPediatric Research
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1440 Child Mortality Under Five in Latvia, Causal Relationship and Reduction Possibilities in An International Context

2010

Background and aims: To identify the reasons of the continuously highest infant and under five mortality (U5M) rates in Latvia (since restoration of independence) within EU - 25, in order to find solutions to minimize the mortality rate in accordance with Millenium Development Goals (MDG). Methods: Analytical study of statistical data bases was performed by monitoring reports, private publications to find causal relationship in international aspect between U5M in Latvia and following factors: GDP, health budget per capita, Gini coefficient, medical service availability, etc. Results: Structure of U5M in Latvia differs from EU-25, being 2 to 10 times higher by reason of external causes of de…

education.field_of_studyGini coefficientMortality ratePopulationSudden infant death syndromeInfant mortalityChild mortalityEnvironmental protectionPediatrics Perinatology and Child HealthPer capitaDemographic economicsBusinesseducationDeveloped countryPediatric Research
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Aplicación de la clasificación de San Diego en el estudio médico-legal de la Muerte Súbita del Lactante

2020

INTRODUCCIÓN La Muerte Súbita del Lactante (MSL) representa un problema universal y grave. El Síndrome de Muerte Súbita del Lactante (SMSL) es la primera causa de muerte en lactantes durante el primer año de vida en países desarrollados y se define como la muerte súbita e inesperada de un lactante, que ocurre durante el sueño y permanece inexplicada tras la realización de una completa investigación postmortem (autopsia con análisis complementarios, examen del lugar de la muerte y revisión de la historia clínica). De esta definición se desprende la clasificación de San Diego basada en las categorías IA, IB y II. Tiene una patogénesis compleja y heterogénea, siendo la teoría del triple riesgo…

sudden infant death syndromeSUDIasphyxiasleeping environmentprone sleep position:CIENCIAS MÉDICAS [UNESCO]overlayingco-sleepingdeath scene investigationautopsyUNESCO::CIENCIAS MÉDICASSIDSrisk factorsbed sharingSUIDaccidental suffocation and strangulation in bed (ASSB)
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